Sample Cleanup: Method Development for Solid Phase Extraction and Beyond

Contaminants in the sample matrix can create chromatography issues, system downtime, and unreliable test results. Having clean samples can help prevent most of these problems. There are many options for sample cleanup.

We’ll discuss the following options:

• Solid phase extraction (SPE), which provides the cleanest sample.

• “Targeted” filtration, which can remove specific interferences from the sample matrix and provides clean samples.

In this talk, we’ll discuss tips for selecting, developing, and implementing SPE methods. We’ll also discuss newly developed targeted filtration options and their benefits.

Presenter: Golnar Javadi (Application Engineer, Agilent Technologies, Inc.)

Golnar Javadi is an applications engineer providing online applications assistance and technical support for LC columns and supplies, Sample Preparation products, and Spectroscopy supplies.

Before joining Varian and then Agilent, Golnar worked in the pharmaceutical and nutraceutical industries on method development and quality control. She also taught college level chemistry courses for a few years.

Golnar then joined Varian as a technical support specialist, providing customers with method development assistance and technical support on Sample Preparation (SPE, SLE, and Filtration), HPLC, GC, ToxiLab and DAT. After the Varian-Agilent merger, Golnar joined Agilent Technologies as an Applications Engineer. She provides technical support to customers on Sample Preparation products, Liquid Chromatography columns, and Spectroscopy supplies.